This graphical abstract for Science illustrates a de novo computational protein design method for epitope-focused immunogens, which were then tested in vivo in primates. Using a cocktail of three computationally designed proteins, Sesterhenn et al. elicit virus neutralizing antibodies in primates.
Publication:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Fabian Sesterhenn et al.Science
